N-[O-Phosphono-Pyridoxyl]-Isoleucine

N-[O‑Phosphono‑Pyridoxyl]‑Isoleucine is an experimental small molecule compound structurally related to pyridoxamine 5'-phosphate and isoleucine. It has been studied primarily as a biochemical probe and inhibitor in research settings, particularly for its interaction with aminotransferase enzymes such as human mitochondrial branched chain aminotransferase (hBCATm). The compound mimics the structure of enzyme intermediates involving pyridoxal phosphate and amino acids, allowing it to act as a competitive inhibitor or mechanistic probe in enzymology studies. There are no approved therapeutic indications or clinical uses for this molecule[1][2][10].

Other names

N-(O-Phosphono-Pyridoxyl)-Isoleucine(2R,3S)-2-(((3-hydroxy-2-methyl-5-(phosphonooxy)methyl)pyridin-4-yl)methyl)amino)-3-methylpentanoic acid(2R,3S)-2-[({3-hydroxy-2-methyl-5-(phosphonooxy)methyl]pyridin–4–yl}methyl)amino]-3-methylpentanoic acidN-[O-PHOSPHONO-PYRIDOXYL]-ISOLEUCINEN-{3-hydroxy–2–methyl–5–[(phosphonooxy)methyl]pyridin–4–yl}methyl-D-alloisoleucine